Lefthanded relief pitcher Craig Breslow is returning to the Twins.

Considered a baseball “loogy” — a “lefthanded one-out guy” — Breslow has pitched only 535 innings despite 539 appearances. He is 22-29 with a 3.35 ERA, 419 strikeouts and 212 walks.

The 11-year veteran agreed to a minor league deal, Fox Sports reported Wednesday, meaning the Twins will not have to clear room on their 40-man roster.

Breslow, 36, pitched in 42 games and had a 1.63 ERA for the Twins in 2008 after being claimed on waivers from Cleveland. He was lost to Oakland on waivers after pitching 17 games for the Twins in 2009. He has also played for the Padres, Marlins, Red Sox and Diamondbacks.

He won a World Series with Boston in 2013, pitching in three World Series games against St. Louis.

Breslow graduated with degrees in molecular biophysics and biochemistry from Yale in 2002, and has been given the nickname “The Smartest Man In Baseball.” He was drafted in the 26th round by Milwaukee that year, and deferred acceptance into medical school to pursue a baseball career.

“The thing that resonated the most with me was the idea that I could impact the culture and impact the direction of the organization for longer than potentially my stay there might be,” Breslow told Fox Sports’ Ken Rosenthal, adding Twins chief baseball officer Derek Falvey is “a really engaging and bright guy with a great vision for the organization. I’ve got no doubt that he’ll be able to be able to bring sustained success. The opportunity to be part of that at this stage of my career is one that is really compelling.”

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